• slidebg1
    Welcome to
    Amplification Technologies
  • slidebg2
    Internationally leading provider of
    RNA technology products
  • slidebg3
    Dedicated to Quality
    of the highest
    international standards

About Us

We are now part of Millipore Sigma

AmpTec has been acquired by Millipore Sigma, a leading science and technology company, based in Germany.

Last year, AmpTec celebrated its fifteenth anniversary, and this acquisition marks an exciting new chapter for our company. AmpTec’s more than 40 employees are thrilled to join Millipore Sigma and are confident that our PCR-based technology and combined expertise will allow us to offer customers innovative technologies, products and services to help advance life-enhancing therapeutics.

view press release

Visit the Millipore Sigma mRNA CDMO Service website for more details on our full offering.

visit Millipore Sigma

We are AmpTec

an internationally leading provider of RNA technology products, including RNA isolation and mRNA amplification kits, synthetic long RNAs and DNAs as well as functional mRNAs.

We are committed to direct and flexible customer interactions with life science industries and academic research institutions around the world, including on-site technical support.

picture of CEOs

AmpTec founders Dr. Peter Scheinert and Dr. Guido Krupp

is our focus

Our products meet the requirements of the finest international standards:

  • Provider of IVT-RNAs since 1998
  • Provider of synthetic Nucleic Acids for worldwide leading Companies in the field of molecular diagnostics and biotechnology
  • Manufacturer in compliance with ISO 13485 since 2010
  • Implementation of cGMP FDA 21 CFR Part 211 and ICH Q7 (section 19: APIs for use in clinical trials) requirements in advanced state

We have implemented a quality management system, certified by DQS MED.

View Certificate (EN)

News & Dates

"Messenger ribonucleic acid (mRNA) in the context of Covid-19: Vaccines, therapies and diagnostics"

Recording of the 5th edition of the online update hygiene and infection prevention powered by MedWiss4you, Dr. Brill + Dr. Steinmann and HIHeal.

view video

"Facing the challenge of Covid-19 with help from mRNA"

AmpTec has been invited as a guest speaker to the Virtual Conference Science Against SARS CoV-2 organized by ThermoFisher Scientific. Many thanks again to the whole team from Thermofisher Scientific for this invitation and for the excellent organization of this webinar. It was great being part of it.

open document

inside AmpTec
AmpTec employees give a helping hand

In this coverage (in German only) AmpTec employees report about their non-profit team event, giving a helping hand to a home for the handicapped, where they worked on building both a garden house and their team spirit.

open document

"Addressing new challenges for large volume mRNA manufacturing "

Thermo Fisher Scientific Speakers &
Peter Scheinert, CEO, AmpTec

open document

In the Media
"A Shot in the Arm for mRNA Vaccines"

Sponsored Feature from Thermofisher Scientific with interview "The Customer View" from AmpTec

In the Media
"Facing The Challange of COVID-19"

Interview with CEO Dr. Peter Scheinert in the online Magazine of LifeScience Nord

LifeScience Nord

Press Release
AmpTec signs agreement for process development of large scale therapeutic mRNA purification

Press Release
Synthetic SARS-CoV-2 Protein mRNAs for vaccination

AmpTec now offers fast track option for manufacturing of synthetic, fully functional SARS-CoV-2 Protein mRNAs for vaccination approaches in cell culture, animal models, preclinical- and Phase I clinical trials.

Press Release
AmpTec as GMP-manufacturer of Positive control IVT RNA for European Commission supporting reliable COVID-19 diagnostics in the EU

In the Media
"cGMP-RNAs for diagnostic"

The German magazine "transkript" reports about AmpTec's contribution to COVID-19 diagnostics.
(German version only)

open document

Meet AmpTec at
TIDES: Oligonucleotide and Peptide Therapeutics

May 11 - 14, 2020
John B. Hynes Veterans Memorial Convention Center, Boston, USA

Meet AmpTec at
8th International mRNA Health Conference

November 9-10, 2020
Boston Park Plaza Hotel, USA

mRNA Conference

In the Media
AmpTec featured in "Guide to German Biotech Companies 2020"

This edition presents nearly 120 companies in the German living biotech industry with a focus on research and development as well as service providers in the life sciences with detailed company portraits in English.

open document

In the Media
AmpTec portrayed as CMO for mRNAs in Life Science North Magazine

The magazine reports on current developments, technologies and people in the life sciences in Hamburg and Schleswig-Holstein. In a special, a topic is discussed in detail, business news are displayed in the section Business North, and in the series Portrait and Talent of the North, attention is drawn to noteworthy persons and institutions. An international English-language edition will be published each autumn.

open document

Press Release
Gritstone Oncology Announces First Patient Dosed with SLATE, its “Off-The-Shelf” Neoantigen

Immunotherapy: Mention of AmpTec as CMO of mRNA technology products

open document

In the Media
AmpTec portrayed as CMO for mRNAs

An article about AmpTec was published in "transkript", which is the leading industry journal for biotechnology and life sciences in German-speaking Europe since 1995. The focus is on up-to-date information, opinions and background information from business, research and industry.

open document

Meet AmpTec at
7th International mRNA Health Conference

November 11-12, 2019
Hilton Hotel Berlin, Berlin, Germany

In the Media
AmpTec portrayed as a "pearl of Hamburg"

An article about AmpTec was published in "Laborjournal", a German service magazine for medicine and life sciences, in which AmpTec was titled to be a "Pearl of Hamburg".

open magazine

Meet AmpTec at
6th International mRNA Health Conference

November 12-13, 2018
Royal Sonesta Boston / Cambridge, MA, USA

Meet AmpTec at
EuroTIDES: Part of TIDES Europe

6th – 9th November 2018
Postillion Convention Center, Amsterdam
4 Days | 2 Co-Located Events

Meet AmpTec at
TIDES Oligonucleotide and Peptide Therapeutics

May 7-10, 2018
Hynes Convention Center, Boston, MA

Meet AmpTec at
Molecular Med TRI-CON 2018

February 11-16, 2018
San Francisco, CA, USA

Meet AmpTec at
International mRNA Health Conference

November 1st-2nd, 2017
Berlin, Germany

Meet AmpTec at
Molecular Med TRI-CON 2017

February 19-24, 2017
San Francisco, CA, USA

Press Release
CMC Pharma and AmpTec close consulting agreement

CMC Pharma GmbH and AmpTec GmbH close consulting agreement for API-mRNA production according to GMP FDA 21 CFR Part 210, 211, ICH Q7 for IND/CTA use in early phase clinical studies.

Press Release
Scope of certified quality expanded

AmpTec Expands Scope for its quality management system, certified by DQS MED:
New Scope: production and sales of synthetic nucleic acids for diagnostic AND therapeutic use.

view certificate

coming soon
Fill & Finish of mRNAs within our new clean room concept

This solution consists of Class D-C-B-A (EU-GMP-Annex1) or Class 100.000-100 (FDA Aseptic Guide) and is determined for Aseptic Fill & Finish of our mRNAs.

product news
Now available: Stocked mRNA catalogue products

AmpTec now offers stocked mRNA catalogue products from microgram to milligram scale range.

view catalogue

Press Release
New England Biolabs® Announces Agreement with AmpTec GmbH to supply key mRNA Synthesis Reagents

research paper
Synthetic mRNA for manipulating cellular phenotypes

A reseach paper published by Elgar Susanne Quabius and AmpTec CEO Dr. Guido Krupp

read more

Press Release
Eurofins Genomics and AmpTec close distribution agreement for very long synthetic RNAs

Joint expertise to provide custom services for in vitro transcribed (IVT) single-stranded (ss) and double-stranded (ds) RNAs and for functional synthetic mRNAs.

Press Release
Exclusive supply contract with Insight Genetics

Hamburg-based supplier AmpTec and US diagnostic company Insight Genetics sign exclusive supply contract for synthetic reference RNAs.

read more

Partners We proudly team up with strong and qualified partners:

Life Science Nord
eurofins genomics

Our product EURM-019 is a

universal COVID-19

positive control,
accepted by the European Commision

Quality is our focus.


We specialized in the following four product groups:

Guide RNAs for CRISPR
Long RNA Oligos for RNA therapeutics

  • Customized single stranded RNA Oligos up to 140 bases from any sequence
  • Fully enzymatically produced. No abortive products.
  • Any Scale available
    (now from ng to g)
  • Highly standardized enzymatic AmpTec workflow
  • ISO 13485
  • Possible applications
    Guide RNAs for CRISPR
    RNA therapeutics
    RNAi applications
    Short RNA controls

Functional mRNAs
Therapeutic mRNAs

  • Customized functional mRNAs from any sequence
  • Highly modified or unmodified available
  • Implementation of ICH Q7 (Chapter 19) for API in clinical trials compliance
  • Any Scale available
    (now from ng to g)
  • Highly standardized AmpTec workflow
  • ISO 13485 certified
  • Possible applications
    Highly specific vaccination
    Individualized tumor therapy with tissue-specific and patient-specific tumor markers/antigens (anti-viral therapy)
    Stem cells by cellular reprogramming
    Cell therapy with in vitro generated tissue autologous, patient-derived tissue cells (see Quabius & Krupp, 2014 )
  • Now available:
    Stocked mRNA catalogue products from microgram to milligram scale range

Long ssRNAs and dsRNAs and DNAs

  • Customized long RNAs and DNAs from any sequence for in vitro diagnostics or companion diagnostics
  • High quality IVT-RNA and DNA in any length and scale
  • Highly standardized AmpTec workflow
  • Possible applications
    Reference material for SARS-CoV-19 positive control, accepted by the European Commission
    Internal control RNA for performance control (e.g. RNA isolation, reverse transcription and qPCR amplification / detection
    Positive control RNAs for controlling high assay qualities

Functional dsRNAs

  • Customized functional dsRNAs from any sequence
  • Any Scale available (from ng to mg)
  • Direct dsRNA synthesis procedure, not by annealing of two ssRNAs
  • Highly standardized AmpTec workflow
  • Possible applications
    Double-strand RNA (dsRNA) as tool for gene-specific silencing of gene expression
    Long dsRNA is substantially more effective than short dsRNA
    Indirect introduction of long dsRNA in diverse organisms
    Direct injection of long dsRNA in oysters as prominent example

Additional products

  • ExpressArt® RNA Isolation Kits:
    unique technology for RNA isolation
  • ExpressArt® mRNA Amplification Kits:
    patented technology for universal amplification of even highly degraded mRNAs
  • Patented technology for bacterial mRNA amplification
  • Picograms of total RNA input sufficient
  • Possible applications
    Reliable high quality RNA-Isolation from FFPE-material
    Universal pre-amplification of mRNAs for Transcriptome Analysis
    Universal pre-amplification of mRNAs for Next generation Sequencing Analysis (NGS)


AmpTec is a dynamically growing company with a highly motivated team.
If you are interested in joining us, please contact us. You will find our details below.

Contact Us

Get in touch with us. We take great effort in our customer service. Please do not hesitate to call.

Dr. Peter Scheinert, CEO
Dr. Peter Scheinert

Managing Director

Dr. Guido Krupp, CEO

Dr. Guido Krupp

Senior research fellow


  • AmpTec GmbH
    Koenigstr. 4A
    D-22767 Hamburg

Call Us

Quick Contact

Hamburg harbour

Get In Touch

Your Name *
Your Email *
Your Message *